References

Abrams BE, Hottinger H, Selmic LE Use of regional limb perfusion with amikacin sulphate in the treatment of a severe soft tissue infection in the extremity of a dog. Vet Rec Case Rep. 2019; 7:(1) https://doi.org/10.1136/vetreccr-2018-000777

Bennett D, May C Joint diseases of dogs and cats, 3rd edn. (eds). Philadelphia: WB Saunders; 1995

Bubenik LJ, Smith MM Orthopaedic infections, 3rd edn. In: Slatter D (ed). Philadelphia: Saunders; 2003

Carr AP Infectious arthritis in dogs and cats. Vet Med. 1997; 92:786-797

Clements D Arthrocentesis and synovial fluid analysis in dogs and cats. In Practice. 2006; 28:(5)256-262 https://doi.org/10.1136/inpract.28.5.256

Clements DN, Owen MR, Mosley JR, Carmichael S, Taylor DJ, Bennett D Retrospective study of bacterial infective arthritis in 31 dogs. J Small Anim Pract. 2005; 46:(4)171-176 https://doi.org/10.1111/j.1748-5827.2005.tb00307.x

Clements DN, Bennett D Bacterial infective arthritis: an uncommon condition? Mr D Clements and Professor D Bennet respond. J Small Anim Pract. 2005; 46:(6)

Dolganiuc A, Stavaru C, Anghel M, Baltaru D, Georgescu E, Olinescu A The migratory and phagocytic activity of polymorphonuclear leukocytes in rheumatoid arthritis and osteoarthritis patients. Roum Arch Microbiol Immunol. 2000; 59:(1–2)43-53

Fischer C, Cuddy LC, McNally T Spontaneous septic arthritis in juvenile dogs. Ir Vet J. 2020; 10:(8)428-430

Fitch RB, Hogan TC, Kudnig ST Hematogenous septic arthritis in the dog: results of five patients treated nonsurgically with antibiotics. J Am Anim Hosp Assoc. 2003; 39:(6)563-566 https://doi.org/10.5326/0390563

Hayes G, Gibson T, Moens NM Intra-articular implantation of gentamicin impregnated collagen sponge causes joint inflammation and impaired renal function in dogs. Vet Comp Orthop Traumatol. 2016; 29:(2)159-163 https://doi.org/10.3415/VCOT-15-05-0088

Innes JF Arthritis. In: Tobias KM, Johnston SA (eds). St Louis: Elsevier; 2011

Jerosch J, Prymka M Arthroscopic therapy of septic arthritis. Surgical technique and results. Unfallchirurg. 1998; 101:(6)454-460 https://doi.org/10.1007/s001130050295

Lazarus MA, Kim SE, Lewis DD, Johnson MD Intra-articular injection of a dextran Polymer combined with antibiotic medications for bacterial infective arthritis in dogs: 14 cases. Vet Comp Orthop Traumatol. 2021; 4:(02)e104-e110 https://doi.org/10.1055/s-0041-1739460

Marchevsky AM, Read RA Bacterial septic arthritis in 19 dogs. Aust Vet J. 1999; 77:(4)233-237 https://doi.org/10.1111/j.1751-0813.1999.tb11708.x

Mielke B, Comerford E, English K, Meeson R Spontaneous septic arthritis of canine elbows: twenty-one cases. Vet Comp Orthop Traumatol. 2018; 31:(6)488-493 https://doi.org/10.1055/s-0038-1668108

Newman RJ, Chow L, Goodrich LR, Lambrechts NE, Dow SW, Pezzanite LM Susceptibility of canine chondrocytes and synoviocytes to antibiotic cytotoxicity in vitro. Vet Surg. 2021; 50:(3)650-658 https://doi.org/10.1111/vsu.13591

Phillips TF, Bleyaert HF Retrospective evaluation of 103 cases of septic arthritis in dogs. Vet Rec. 2022; 190:(5) https://doi.org/10.1002/vetr.938

Ramsey I BSAVA small animal formulary, 8th edn. Gloucester: British Small Animal Veterinary Assocation; 2014

Rubio-Martínez LM, Cruz AM Antimicrobial regional limb perfusion in horses. J Am Vet Med Assoc. 2006; 228:(5)706-655 https://doi.org/10.2460/javma.228.5.706

Scharf VF, Lewis DD, Wellehan JF, Wamsley HL, Richardson R Comparison of synovial fluid culture and 16S rRNA PCR in dogs with suspected septic arthritis. Aust Vet J. 2015; 93:(6)204-207 https://doi.org/10.1111/avj.12329

Scurrell E, Arthurs G Sampling and laboratory investigation. In: Arthurs G, Brown G, Pettitt R (eds). Gloucester: British Small Animal Veterinary Association; 2018

Canine septic arthritis

02 April 2024
9 mins read
Volume 29 · Issue 4

Abstract

Septic arthritis is an important cause of lameness in a broad age range of patients. Diagnosis is based on a combination of the clinical presentation, arthrocentesis sampling and exclusion of alternative causes of lameness. In-house cytology can likely provide a presumptive diagnosis and enable treatment initiation while awaiting a culture result. Although there is poor evidence for treatment recommendations, the prognosis is likely good with prompt treatment. However, clinicians should make owners aware that there is a risk of recurrence and there may be a limited recovery in patients with pre-existing osteoarthritis.

Septic arthritis is a relatively uncommon cause of lameness in the canine population (Bubenik and Smith, 2003); however, it is important to recognise this condition to minimise the chances of permanent damage and persistent lameness. Septic arthritis can be divided into two major aetiologies: haematogenous infections and direct inoculation of the joint via trauma or surgery.

Haematogenous arthritis can be initiated by a spread of infection from a focus elsewhere in the body, for example dermatitis or otitis, or spontaneously where a distant source of bacteria is not identified. In adult animals, haematogenous infections are often seen in a joint with pre-existing osteoarthritis, which is presumed to be related to the increased vascularisation of the affected joint aiding in bacterial invasion (Clements et al, 2005), while human healthcare literature suggests that neutrophils within osteoarthritic joints may have reduced motility and efficacy, potentially leading to reduced bacterial clearance (Dolganiuc et al, 2000). A thorough clinical examination is required to locate a potential primary focus of infection and allow differentiation from a true ‘spontaneous’ case.

Register now to continue reading

Thank you for visiting UK-VET Companion Animal and reading some of our peer-reviewed content for veterinary professionals. To continue reading this article, please register today.