References

Marvel SJ, Goldblatt B, MacPhail CM, Zersen KM The use of a novel nitric oxide wound dressing in acute traumatic wounds in dogs. Am J Vet Res.. 2024; 85:(9) https://doi.org/10.2460/ajvr.24.04.0124

Noxsano. Case studies. 2024. https://www.noxsano.com/case-study

Rodriguez-Diaz JM, Wallace ML, Emond SA, McNabney D, Hodges KM, Howerth EW Effect of hydrocolloidnitric oxide wound dressings on wound healing in dogs. Vet Surg.. 2024; 53:(8)1351-1365 https://doi.org/10.1111/vsu.14149

Noxsano's innovative wound care solutions

02 April 2025
3 mins read
Volume 30 · Issue 4
Figure 1. 
Grey hue of tissues following the use of the gel formulation. A) The wound at the time of presentation following clipping and lavage. B) The wound following placement of the activated gel formulation. C) The wound 2 days later, post lavage. Closure was performed at this visit, and healing was uncomplicated.
Figure 1. Grey hue of tissues following the use of the gel formulation. A) The wound at the time of presentation following clipping and lavage. B) The wound following placement of the activated gel formulation. C) The wound 2 days later, post lavage. Closure was performed at this visit, and healing was uncomplicated.

Abstract

Effective wound management is a cornerstone of veterinary care, aiming to accelerate healing, prevent infections and ensure the wellbeing of patients. Noxsano Animal Health has introduced ground-breaking products – Restore Wound Pads and Gels – that harness the power of nitric oxide to revolutionise wound treatment in veterinary medicine.

Injuries and surgical incisions in animals necessitate prompt and efficient healing to minimise stress and reduce the risk of infection. While human medicine offers advanced wound care therapies, their high costs often render them impractical for veterinary applications. This disparity highlights the need for affordable, yet effective solutions tailored to the unique requirements of veterinary patients.

Nitric oxide is a naturally occurring molecule integral to various physiological processes, including wound healing. Its functions include:

These multifaceted functions position nitric oxide as a pivotal agent in the body's natural wound-healing cascade.

The following studies have confirmed the efficacy of nitric oxide-releasing wound dressings in promoting faster healing and reducing infection risks:

These findings reinforce Noxsano's claim that their Restore wound pads and gels optimise healing conditions and improve clinical outcomes.

Recognising the therapeutic potential of nitric oxide, Noxsano developed a cost-effective method to deliver nitric oxide directly to the wound site. By using sodium nitrite, a common and inexpensive compound, Noxsano's products generate nitric oxide on activation with water. This on-demand production ensures a sustained release of biologically relevant levels of nitric oxide over several days, optimising the wound healing environment.

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