References

Apelt D, Kowaleski MP, Boudrieau RJ Effect of tibial tuberosity advancement on cranial tibial subluxation in canine cranial cruciate-deficient stifle joints: an in vitro experimental study. Vet Surg. 2007; 36:(2)170-177 https://doi.org/10.1111/j.1532-950X.2007.00250.x

Aragosa F, Caterino C, Della Valle G, Fatone G Tibial tuberosity advancement techniques (TTAT): a systematic review. Animals (Basel). 2022; 12:(16) https://doi.org/10.3390/ani12162114

Bergh MS, Sullivan C, Ferrell CL, Troy J, Budsberg SC Systematic review of surgical treatments for cranial cruciate ligament disease in dogs. J Am Anim Hosp Assoc. 2014; 50:(5)315-321 https://doi.org/10.5326/JAAHA-MS-6356

Bernardi-Villavicencio C, Jimenez-Socorro AN, Rojo-Salvador C, Robles-Sanmartin J, Rodriguez-Quiros J Short-term outcomes and complications of 65 cases of porous TTA with flange: a prospective clinical study in dogs. BMC Vet Res. 2020; 16:(1) https://doi.org/10.1186/s12917-020-02469-2

Boudrieau RJ Tibial plateau leveling osteotomy or tibial tuberosity advancement?. Vet Surg. 2009; 38:(1)1-22 https://doi.org/10.1111/j.1532-950X.2008.00439.x

Brioschi V, Arthurs GI Cranial cruciate ligament rupture in small dogs (<15 kg): a narrative literature review. J Small Anim Pract. 2021; 62:(12)1037-1050 https://doi.org/10.1111/jsap.13404

Bruce WJ, Rose A, Tuke J, Robins GM Evaluation of the triple tibial osteotomy. A new technique for the management of the canine cruciate-deficient stifle. Vet Comp Orthop Traumatol. 2007; 20:(3)159-168 https://doi.org/10.1160/vcot-06-06-0054

Comerford E, Forster K, Gorton K, Maddox T Management of cranial cruciate ligament rupture in small dogs: a questionnaire study. Vet Comp Orthop Traumatol. 2013; 26:(6)493-497 https://doi.org/10.3415/VCOT-12-06-0070

Cosenza G, Reif U, Martini FM Tibial plateau levelling osteotomy in 69 small breed dogs using conically coupled 1.9/2.5 mm locking plates. A clinical and radiographic retrospective assessment. Vet Comp Orthop Traumatol. 2015; 28:(5)347-354 https://doi.org/10.3415/VCOT-14-09-0135

Coskun Ö, Viskjer S Evaluating the outcome after center of rotation of angulation (CORA)-based leveling osteotomy (CBLO) technique to repair unilateral cranial cruciate ligament deficiency using a pressure-sensitive walkway system. Can J Vet Res. 2023; 87:(2)157-164

Duerr FM, Martin KW, Rishniw M, Palmer RH, Selmic LE Treatment of canine cranial cruciate ligament disease. A survey of ACVS Diplomates and primary care veterinarians. Vet Comp Orthop Traumatol. 2014; 27:(6)478-483 https://doi.org/10.3415/VCOT-14-03-0047

Dyall B, Schmökel H Tibial tuberosity advancement in small-breed dogs using TTA Rapid implants: complications and outcome. J Small Anim Pract. 2017; 58:(6)314-322 https://doi.org/10.1111/jsap.12654

Entoft J, Skytte D, Schmökel H, Dyall B Complications and outcome of cranial cruciate ligament disease in small dogs treated with tiny tta rapid. VCOT Open. 2023; 6:(2)e143-e149 https://doi.org/10.1055/s-0043-1771231

Ferreira AJA, Bom RM, Tavares SO Tibial tuberosity advancement technique in small breed dogs: study of 30 consecutive dogs (35 stifles). J Small Anim Pract. 2019; 60:(5)305-312 https://doi.org/10.1111/jsap.12991

Harasen G Canine cranial cruciate ligament rupture in profile. Can Vet J. 2003; 44:(10)845-846

Harasen G Canine cranial cruciate ligament rupture in profile: 2002–2007. Can Vet J. 2008; 49:(2)193-194 https://doi.org/10.4141/cjas69-029

Hoffmann DE, Miller JM, Ober CP, Lanz OI, Martin RA, Shires PK Tibial tuberosity advancement in 65 canine stifles. Vet Comp Orthop Traumatol. 2006; 19:(4)219-227

Jeong J, Jeong SM, Kim SE, Lewis DD, Lee H Subsequent meniscal tears following tibial tuberosity advancement and tibial plateau leveling osteotomy in dogs with cranial cruciate ligament deficiency: An in vivo experimental study. Vet Surg. 2021; 50:(5)966-974 https://doi.org/10.1111/vsu.13648

Jerram RM, Walker AM Cranial cruciate ligament injury in the dog: pathophysiology, diagnosis and treatment. N Z Vet J. 2003; 51:(4)149-158 https://doi.org/10.1080/00480169.2003.36357

Kemper M, Koch D, Bass M, Inauen R Revision operation rate after 214 tibial tuberosity advancements as therapy for anterior cruciate ligament tears in dogs. Schweiz Arch Tierheilkd. 2011; 153:(3)131-133 https://doi.org/10.1024/0036-7281/a000168

Kennedy SC, Dunning D, Bischoff MG, Kuriashkin IV, Pijanowski GJ, Schaeffer DJ The effect of axial and abaxial release on meniscal displacement in the dog. Vet Comp Orthop Traumatol. 2005; 18:(4)227-234

Kowaleski MP, Boudrieau RJ, Pozzi A Stifle joint. In: Tobias KM, Johnston SA (eds). Veterinary surgery: small animal, 2nd edn. St Louis: Elsevier; 2018

Kuroki K, Cook CR, Cook JL Subchondral bone changes in three different canine models of osteoarthritis. Osteoarthritis Cartilage. 2011; 19:(9)1142-1149 https://doi.org/10.1016/j.joca.2011.06.007

Lafaver S, Miller NA, Stubbs WP, Taylor RA, Boudrieau RJ Tibial tuberosity advancement for stabilization of the canine cranial cruciate ligament-deficient stifle joint: surgical technique, early results, and complications in 101 dogs. Vet Surg. 2007; 36:(6)573-586 https://doi.org/10.1111/j.1532-950X.2007.00307.x

Liska WD, Doyle ND Canine total knee replacement: surgical technique and one-year outcome. Vet Surg. 2009; 38:(5)568-582 https://doi.org/10.1111/j.1532-950X.2009.00531.x

Luther JK, Cook CR, Cook JL Meniscal release in cruciate ligament intact stifles causes lameness and medial compartment cartilage pathology in dogs 12 weeks postoperatively. Vet Surg. 2009; 38:(4)520-529 https://doi.org/10.1111/j.1532-950X.2009.00520.x

Macias C, Mckee WM, May C Caudal proximal tibial deformity and cranial cruciate ligament rupture in small-breed dogs. J Small Anim Pract. 2002; 43:(10)433-438 https://doi.org/10.1111/j.1748-5827.2002.tb00009.x

Advancement of the tibial tuberosity for the treatment of cranial cruciate deficit of the canine stifle. 2002. https://www.cabidigitallibrary.org/doi/pdf/10.5555/20193219120 (accessed 15 August 2024)

Moore EV, Weeren R, Paek M Extended long-term radiographic and functional comparison of tibial plateau leveling osteotomy vs tibial tuberosity advancement for cranial cruciate ligament rupture in the dog. Vet Surg. 2020; 49:(1)146-154 https://doi.org/10.1111/vsu.13277

Pozzi A, Litsky AS, Field J, Apelt D, Meadows C, Johnson KA Pressure distributions on the medial tibial plateau after medial meniscal surgery and tibial plateau levelling osteotomy in dogs. Vet Comp Orthop Traumatol. 2008; 21:(1)8-14 https://doi.org/10.3415/VCOT-06-12-0099

Pozzi A, Kim SE, Lewis DD Effect of transection of the caudal meniscotibial ligament on medial femorotibial contact mechanics. Vet Surg. 2010; 39:(4)489-495 https://doi.org/10.1111/j.1532-950X.2010.00662.x

Retallack LM, Daye RM A modified Maquet-tibial tuberosity advancement technique for treatment of canine cranial cruciate ligament disease: short term outcome and complications. Vet Surg. 2018; 47:(1)44-51 https://doi.org/10.1111/vsu.12733

Canine cranial cruciate disease: updating our knowledge about pathogenesis and diagnosis. 2013. https://todaysveterinarypractice.com/orthopedics/canine-cranial-cruciate-disease-updating-our-knowledge-about-pathogenesis-diagnosis/ (accessed 15 August 2024)

Roydev R, Goranov N Long-term clinical and goniometric follow-up of TTA rapid surgery in dogs with cranial cruciate ligament rupture. Acta Veterinaria Eurasia. 2021; 47:(3)154-160

Selmi AL, Padilha Filho JG Rupture of the cranial cruciate ligament associated with deformity of the proximal tibia in five dogs. J Small Anim Pract. 2001; 42:(8)390-393 https://doi.org/10.1111/j.1748-5827.2001.tb02487.x

Skinner OT, Kim SE, Lewis DD, Pozzi A In vivo femorotibial subluxation during weight-bearing and clinical outcome following tibial tuberosity advancement for cranial cruciate ligament insufficiency in dogs. Vet J. 2013; 196:(1)86-91 https://doi.org/10.1016/j.tvjl.2012.08.003

Stein S, Schmoekel H Short-term and eight to 12 months results of a tibial tuberosity advancement as treatment of canine cranial cruciate ligament damage. J Small Anim Pract. 2008; 49:(8)398-404 https://doi.org/10.1111/j.1748-5827.2008.00592.x

Vasseur PB, Pool RR, Arnoczky SP, Lau RE Correlative biomechanical and histologic study of the cranial cruciate ligament in dogs. Am J Vet Res. 1985; 46:(9)1842-1854

Vedrine B, Guillemot A, Fontaine D, Ragetly GR, Etchepareborde S Comparative anatomy of the proximal tibia in healthy Labrador Retrievers and Yorkshire Terriers. Vet Comp Orthop Traumatol. 2013; 26:(4)266-270 https://doi.org/10.3415/VCOT-12-02-0018

Voss K, Damur DM, Guerrero T, Haessig M, Montavon PM Force plate gait analysis to assess limb function after tibial tuberosity advancement in dogs with cranial cruciate ligament disease. Vet Comp Orthop Traumatol. 2008; 21:(3)243-249

Wemmers AC, Charalambous M, Harms O, Volk HA Surgical treatment of cranial cruciate ligament disease in dogs using tibial plateau leveling osteotomy or tibial tuberosity advancement – s systematic review with a meta-analytic approach. Front Vet Sci. 2022; 9 https://doi.org/10.3389/fvets.2022.1004637

Whitehair JG, Vasseur PB, Willits NH Epidemiology of cranial cruciate ligament rupture in dogs. J Am Vet Med Assoc. 1993; 203:(7)1016-1019

Witte PG Tibial anatomy in normal small breed dogs including anisometry of various extracapsular stabilizing suture attachment sites. Vet Comp Orthop Traumatol. 2015; 28:(5)331-338 https://doi.org/10.3415/VCOT-14-12-0186

Zhalniarovich Y, Sobolewski A, Waluś G, Adamiak Z Evaluation, description of the technique, and clinical outcomes after tibial tuberosity advancement with cranial fixation (TTA CF) for cranial cruciate ligament rupture in 22 dogs. Top Companion Anim Med. 2018; 33:(3)65-72 https://doi.org/10.1053/j.tcam.2018.07.003

Tibial tuberosity advancement as a treatment option for cranial cruciate ligament disease

02 January 2025
11 mins read
Volume 30 · Issue 1

Abstract

Tibial tuberosity advancement as a treatment option for cranial cruciate ligament disease was developed and introduced in 2002. Since then, several different implants have been developed to improve the technique and reduce the complication rate. Studies into the outcomes of this procedure report a lower rate of both minor and major complications and good to excellent overall function (outcome and lameness) in more than 90% of dogs, as reported by the owners. Tibial tuberosity advancement is a procedure comparable with alternate osteotomy methods of cranial cruciate ligament repair with expected good to excellent functional outcome in a variety of dogs with proper case selection. Dogs with a distal patellar ligament insertion point, an excessive tibial plateau angle and angular and/or torsional limb deformities may be more suited for other surgical techniques.

Cranial cruciate ligament disease is one of the most common causes of hindlimb lameness in dogs (Harasen, 2003; 2008; Roush, 2013; Dyall and Schmökel, 2017; Kowaleski et al, 2018). The condition is described as a degenerative and progressive weakening of the ligament, and the pathology behind the degeneration is not yet fully understood (Kowaleski et al, 2018). Several risk factors have been described in the development of cranial cruciate ligament disease, including breed predisposition, obesity and gender/neutering status, with neutered females of large breeds being over-represented (Vasseur et al, 1985). Studies have also found a correlation between a high tibial plateau angle and the development of cranial cruciate ligament disease (Macias et al, 2002; Cosenza et al, 2015). However, studies by Witte (2015) and Vedrine et al (2013) did not show such a correlation, signifying the unlikeliness of a high tibial plateau angle as the sole causative factor for cranial cruciate ligament rupture in small-breed dogs.

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